3D Bioprinting of heterogeneous aortic valve conduits with alginate/gelatin hydrogels

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3D bioprinting of heterogeneous aortic valve conduits with alginate/gelatin hydrogels.

Heart valve disease is a serious and growing public health problem for which prosthetic replacement is most commonly indicated. Current prosthetic devices are inadequate for younger adults and growing children. Tissue engineered living aortic valve conduits have potential for remodeling, regeneration, and growth, but fabricating natural anatomical complexity with cellular heterogeneity remain c...

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As the biocompatible materials, hydrogels have been widely used in three- dimensional (3D) bioprinting/organ printing to load cell for tissue engineering. It is important to precisely control hydrogels deposition during printing the mimic organ structures. However, the printability of hydrogels about printing parameters is seldom addressed. In this paper, we systemically investigated the printa...

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3D bioprinting of vascularized, heterogeneous cell-laden tissue constructs.

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ژورنال

عنوان ژورنال: Journal of Biomedical Materials Research Part A

سال: 2012

ISSN: 1549-3296

DOI: 10.1002/jbm.a.34420